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P2-153: SIRT1 is decreased in Alzheimer's disease and correlates with tau pathology

✍ Scribed by Julien, Carl; Tremblay, Cyntia; Phivilay, Alix; Rancourt, Caroline; Calon, Frédéric


Book ID
122573102
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
57 KB
Volume
4
Category
Article
ISSN
1552-5260

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Decreased drebrin mRNA expression in Alz
✍ Carl Julien; Cyntia Tremblay; Farid Bendjelloul; Alix Phivilay; Marie-Andrée Cou 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB

## Abstract To investigate the mRNA expression of the dendritic spine protein drebrin in Alzheimer's disease (AD), we performed post‐mortem in situ hybridization studies in brain sections from 20 AD patients and 21 controls. AD diagnosis was confirmed by decreased drebrin protein and increased Aβ~4