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P.1.e.005 Measurement of brain iron in patients with Parkinson's disease using susceptibility weighted imaging

✍ Scribed by J. Yang; J. Zhang; B. Zhang; P. Svenningsson

Book ID
118598192
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
59 KB
Volume
21
Category
Article
ISSN
0924-977X

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Postmortem demonstration of increased iron in the substantia nigra (SN) is a well-appreciated finding in Parkinson's disease (PD). Iron facilitates generation of free radicals, which are thought to play a role in dopamine neuronal loss. To date, however, magnetic resonance imaging (MRI) has failed t