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P1a Promoter methylation of the BRCA1 gene in young breast cancer patients with no significant family history

✍ Scribed by A.M. Gutierrez-Barrera; J. Litton; G.N. Hortobagyi; B.K. Arun

Book ID
119601743
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
168 KB
Volume
8
Category
Article
ISSN
1359-6349

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Inherited susceptibility to breast cancer results from germline mutations in one of a number of genes including BRCA1. A significant number of BRCA1-linked familial breast cancer patients, however, have no detectable BRCA1 mutation. This could be due in part to the inability of commonly used mutatio