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P19-20. Allogeneic stimulation of the anti-viral APOBEC3G in human CD4+ T cells and prevention of SHIV infectivity in macaques immunized with HLA antigens

✍ Scribed by Y Wang, T Whittall, J Scholler, R Wyatt, M Singh, LA Bergmeier, E Bunnik…

Book ID: 120692327
Publisher: BioMed Central
Year: 2009
Tongue: English
Weight: 66 KB
Volume: 6
Category: Article
ISSN: 1742-4690
DOI: 10.1186/1742-4690-6-S3-P340

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## Abstract Allogeneic immunity is one of the most potent natural immune responses. APOBEC3G (A3G) is an intracellular anti‐viral factor that deaminates cytidine to uridine. Allogeneic stimulation of human CD4^+^ T cells __in vitro__ upregulated A3G mRNA and a significant correlation was found betw

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