## Abstract The oncogenic transcription factor Stat3 is constitutively active in a high percentage of human tumors including mammary adenocarcinomas and is reported to participate in the ErbBβ2 oncogene signaling. In order to assess the role of signal transducer and activator of transcription 3 (St
p185neu protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma
β Scribed by Patrizia Nanni; Serenella M. Pupa; Giordano Nicoletti; Carla De Giovanni; Lorena Landuzzi; Ilaria Rossi; Annalisa Astolfi; Cinzia Ricci; Roberta De Vecchi; Anna M. Invernizzi; Emma Di Carlo; Piero Musiani; Guido Forni; Sylvie Menard; Pier-Luigi Lollini
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 779 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Cancer cells display high rates of aerobic glycolysis, a phenomenon known as the Warburg effect. Lactate and pyruvate, the end products of glycolysis, are overproduced by cancer cells even in the presence of oxygen. The pentose phosphate pathway (PPP) allows glucose conversion to ribose
## Abstract Merkel cell carcinoma (MCC) is a highly aggressive skin cancer that frequently harbours Merkel cell polyomavirus (MCV) DNA integrated in the genome of the tumor cells. In our study, we elaborate our recent finding that MCVβpositive MCC cell lines require the expression of the viral T an
## Abstract Dyskerin is an essential nucleolar protein required for the biogenesis of ribonucleoproteins that incorporate H/ACA RNAs. Through binding to specific H/ACA RNAs, dyskerin exerts most of its influence in the cell. To that end, dyskerin is a core component of the telomerase complex and is