P171 Influence of favourable and unfavourable genetic prognostic markers and CD 38 expression in chronic lymphocytic leukemia on treatment free interval and overal survival. Single center experience between 2002 2006
✍ Scribed by H. Losonczy; G. Kovács; B. Kajtár; G. Méhes; L. Molnár; M. Dávid; Á. Nagy; Á. Szomor; T. Szendrei; L. Potó; L. Pajor
- Book ID
- 104323223
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 46 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0268-960X
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✦ Synopsis
25/27 patients are alive, while 2 patients died before D100. 15/24 patients reached metabolic remission. All of them are in complete remission at the time of evaluation after a median follow-up time of 515 (range 342 773) days. In 2/8 PETpositive patients rebiopsy proved progression or relapse. In 1/8 patient further scans raised the possibility of false PETpositivity. In additional 1/8 PET-positive patient progression or relapse became clinically evident. In additional 4/8 PET-positive patients rebiopsy and/or further PET-CT scans are planned. A negative PET-CT scan after SCT seems to be a favourable factor for cure in refractory or relapsed HD, but further investigation is needed. However, in the cases of positive post-transplant PET scans, rebiopsy or further (PET-CT) scans are warranted to exclude false positivity.