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P168 Effects of substance P on potassium currents in equine articular chondrocytes

Book ID: 114349112
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 111 KB
Volume: 13
Category: Article
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(05)80513-8

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Chondrocytes experience a dynamic extracellular osmotic environment during normal joint loading when fluid is forced from the matrix, increasing the local proteoglycan concentration and therefore the ionic strength and osmolarity. To exist in such a challenging environment, chondrocytes must possess