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P167 PURINERGIC PATHWAY SUPPRESSES THE RELEASE OF NO AND STIMULATES PROTEOGLYCAN SYNTHESIS IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO DYNAMIC COMPRESSION

✍ Scribed by T.T. Chowdhury; M.M. Knight


Book ID
114349514
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
106 KB
Volume
14
Category
Article
ISSN
1063-4584

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Purinergic pathway suppresses the releas
✍ T.T. Chowdhury; M.M. Knight πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 310 KB

## Abstract Mechanical loading plays a fundamental role in the physiological and pathological processes of articular cartilage. The application of dynamic compression to chondrocytes cultured in agarose, downregulates the release of nitric oxide (NO) and enhances cell proliferation and proteoglycan