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P160 distribution kinetics of salicylic acid in isolated perfused cirrhotic rat liver

โœ Scribed by Nasseri, K.; Rowland, M.


Book ID
122902082
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
130 KB
Volume
2
Category
Article
ISSN
0928-0987

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โœ Bhasker V. Shetty; Mostafa Badr; Srikumaran Melethil ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 220 KB ๐Ÿ‘ 2 views

Hepatic metabolism of salicylic acid was studied using a single-pass liver perfusion technique. Livers obtained from male, Sprague-Dawley rats (200-300 g) were perfused with Krebs-Henseleit bicarbonate buffer containing the drug (50-100 micrograms/mL) and glycine (0.5 or 5 mM) or glucose (5.5 mM) or