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p16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N′-nitro-N-nitrosoguanidine

✍ Scribed by Hua Bai; Liankun Gu; Jing Zhou; Dajun Deng

Book ID
117767072
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
197 KB
Volume
535
Category
Article
ISSN
1383-5718

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The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitroroguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 5 I 2 mg/kg body weight, every other day after 20 weeks of or