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p16 and p53 gene alterations and accumulations in the malignant evolution of intraductal papillary-mucinous tumors of the pancreas

✍ Scribed by Wada, Keita

Publisher: Springer
Year: 2002
Tongue: English
Weight: 161 KB
Volume: 9
Category: Article
ISSN: 0944-1166
DOI: 10.1007/s005340200007

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## Abstract Intraductal papillary‐mucinous tumors (IPMT) consist of cells with varying histologic degrees of severity and exhibit multiple tumor loci; however, whether or not these lesions exhibit the same genetic changes has not been clarified. To investigate this point, we analyzed K‐ras mutation