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P158 Histomorphometric analysis of 4-nitroquinoline-1-oxide induced changes in rat oral and gastrointestinal mucosa

✍ Scribed by Kaplan, I.; Traves, S.; Hirshberg, A.


Book ID
118655898
Publisher
Elsevier Science
Year
2007
Weight
51 KB
Volume
2
Category
Article
ISSN
1744-7895

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## Abstract The alkylating agent 4‐nitroquinoline 1‐oxide (4‐NQO) is a powerful carcinogen and induces squamous cell hyperplasia, squamous cell dysplasia, papilloma, and squamous cell carcinoma (a) in rat oral epithelia. Oral cancers induced by a single application of 4‐NQO develop through a multis