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P144 A CHONDROPROTECTIVE ROLE FOR FGF-2 IN THE PERICELLULAR MATRIX OF ARTICULAR CARTILAGE

โœ Scribed by T.L. Vincent; Y. Sawaji; C. McLean; L. Full; J. Saklatvala

Book ID
114349491
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
40 KB
Volume
14
Category
Article
ISSN
1063-4584

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โœ Vishwas Ganu; Ronald Goldberg; Jane Peppard; John Rediske; Richard Melton; Shou- ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 918 KB

Objective. To determine whether matrix metalloproteinases (MMPs) degrade cartilage oligomeric matrix protein (COMP) to produce fragments similar to those found in synovial fluid (SF) from patients with arthritis. Methods. COMP fragments were generated in vitro by treating (a) bovine articular carti