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P132 HEME OXYGENASE-1 MODULATES INSULIN GROWTH FACTOR-1 AND METALLOPROTEINASES IN OSTEOARTHRITIC CHONDROCYTES

✍ Scribed by M.I. Guillen; J. Megias; F. Gomar; A. Bru; M.J. Alcaraz

Book ID
114349479
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
41 KB
Volume
14
Category
Article
ISSN
1063-4584

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Objective. To investigate insulin-like growth factor 1 (IGF-1) production in normal and osteoarthritis (OA) chondrocytes and to further examine the role of growth hormone (GH) in adult human cartilage and, in particular, in diseased tissue. Methods. IGF-1 production was measured with a radioimmunoa