P129 Early detection of breast cancer in core biopsies bymeans of quantitative RT PCR
โ Scribed by V. Vuaroqueaux; H. Zanetti; M. Labuhn; P. Urban; E. Wight; G. Singer; W. Holzgreve; U. Eppenberger; S. Eppenberger-Castori
- Book ID
- 114315852
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 138 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0960-9776
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Real-time RT-PCR is a relatively new technology that uses an online fluorescence detection system to determine gene expression levels. It has the potential to significantly improve detection of breast cancer metastasis by virtue of its exquisite sensitivity, high throughput capacity and quantitative
## Abstract The aim of our study was to detect micrometastatic breast cancer by epithelial glycoproteinโ2 (EGPโ2) and cytokeratin 19 (CK19), using immunostaining and real time quantitative reverse transcriptaseโpolymerase chain reaction (qRTโPCR). Fiftyโeight breast cancer patients, 52 primary tumo