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P1.28 Acute effects of levodopa administration on cardiovascular responses to tilt test in patients with Parkinsonism

✍ Scribed by P. Guaraldi; G. Calandra-Buonaura; R. Terlizzi; L. Solieri; P. Cortelli

Book ID
116267426
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
78 KB
Volume
149
Category
Article
ISSN
1566-0702

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Effect of entacapone, a COMT inhibitor,
Effect of entacapone, a COMT inhibitor, on the pharmacokinetics of levodopa and on cardiovascular responses in patients with Parkinson's disease
✍ V. V. MyllylΓ€; K. A. Sotaniemi; A. Illi; K. Suominen; T. KerΓ€nen πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 563 KB

In an open, randomised, cross-over study we investigated the effect of a single 200 mg oral dose of entacapone, a novel catechol-O-methyltransferase (COMT) inhibitor, on the pharmacokinetics and metabolism of levodopa/carbidopa, and on the cardiovascular responses (blood pressure and pulse rate vari