P.1.042 Fluoxetine and dothiepin in depressed patients: A comparison of efficacy and effects on cognition and subjective sleep
β Scribed by D.B. Fairweather; N. Stanley; I. Hindmarch
- Book ID
- 118599780
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 146 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0924-977X
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Paroxetine improve the quality of sleep and the ease of waking up on subjective measures of sleep (the LSEQ). Dothiepin in contrast improved the ease of getting to sleep, but caused a reduced quality of sleep and a `hangover' eect the next morning.
The objective of this study was to assess whether there are any dierences between Β―uoxetine and dothiepin on cognitive function of patients with major depression (DSMIII-R). A randomized, double-blind, parallel group design, 6 week trial in patients in general practice was employed where patients we