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P1-54 Maternal and child glutathione-S-transferase M1 and T1 polymorphisms modify effect of maternal smoking in pregnancy on childhood lung function

✍ Scribed by A.J. Henderson; R.B. Newson; J.W. Holloway; M.J. Rose-Zerilli; M.E. Pembrey; S.M. Ring; S.O. Shaheen

Book ID
114247421
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
51 KB
Volume
83
Category
Article
ISSN
0378-3782

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## Abstract ## Objective Glutathione S‐transferase (GST) genes as well as heme oxygenase 1 gene (HMOX1) encode enzymes that detoxify carcinogens and protect against oxidative stress. This study was undertaken to examine the impact of gene–smoking interactions on susceptibility to rheumatoid arthri