P1-367 Tolerability, safety and efficacy in patients with Alzheimer's disease who are switched from donepezil to galantamine
β Scribed by Alexander F. Kurz; Michael Gold
- Book ID
- 117413240
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 286 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0197-4580
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This study investigates the tolerability, safety and efficacy of abrupt or stepwise switching from donepezil to memantine treatment in patients with moderate-to-severe Alzheimer's disease (AD). Outpatients (Table 1), !50 years, with dementia of the Alzheimer's type (DSM-IV-TR), MMSE 18 and receiving
## Abstract ## Background There have been very limited investigations of cholinesterase inhibitor therapy in more advanced stages of Alzheimer's disease (AD). The efficacy and safety of donepezil were evaluated in __post hoc__ analyses of a subgroup of patients with more severe AD (standardized Mi