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P1-075: 3d whole-brain perfusion MRI in APP Transgenic mice

✍ Scribed by James S. Curtis; Hasan J. Cakiroglu; Simone Zehntner; Edith Hamel; Barry J. Bedell

Book ID: 118464247
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 111 KB
Volume: 4
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2008.05.661

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## Abstract Clinical magnetic resonance imaging (MRI) offers a noninvasive diagnostic tool for neurodegenerative diseases. MRI was performed on mice to investigate a relationship between brain atrophy and overexpression of two genes involved in such diseases, SOD1 (superoxide dismutase) and APP (am