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P045: Prognostic Value of Lymph Node Metastasis in Head and Neck

✍ Scribed by Eduardo Busto; Cecilia Parisini; Carlos Froilan Soria; Ana Alceste Morandi


Book ID
116811736
Publisher
SAGE Publications
Year
2006
Tongue
English
Weight
49 KB
Volume
135
Category
Article
ISSN
0194-5998

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Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase