P.021 Native conformation and wild-type sequence of Epstein–Barr virus protein BARF1 are essential for humoral immune responses to BARF1 in nasopharyngeal carcinoma patients

Spontaneous T cell responses to Epstein-

Spontaneous T cell responses to Epstein-Barr virus-encoded BARF1 protein and derived peptides in patients with nasopharyngeal carcinoma: Bases for improved immunotherapy

✍ Debora Martorelli; Karim Houali; Laura Caggiari; Emanuela Vaccher; Luigi Barzan; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 231 KB 👁 1 views

## Abstract Immunotherapy approaches targeting Epstein‐Barr virus (EBV)‐encoded antigens induce objective clinical responses only in a fraction of patients with undifferentiated nasopharyngeal carcinoma (UNPC). In the present study, we have characterized the immunogenicity of the EBV‐encoded BARF1