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P013. Nitric oxide synthase establishes a local nitric oxide gradient regulating S-nitrosylation and protein secretion

✍ Scribed by Yasuko Iwakiri; Ayano Satoh; Suvro Chatterjee; Vijay Shah; Derek Toomre; Cecile M. Chalouni; David Fulton; Roberto Groszmann; William C. Sessa

Book ID: 116790115
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 83 KB
Volume: 14
Category: Article
ISSN: 1089-8603
DOI: 10.1016/j.niox.2006.04.072

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## Abstract Expression of inducible nitric oxide synthase (iNOS), which leads to the production of nitric oxide (NO), is stimulated by proinflammatory cytokines such as interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α). Here we report on the roles of nuclear factor‐κB (NF‐κB) and mitogen‐a