P002 SERO-REACTIVITY TO MICROBIAL COMPONENTS IN CROHN'S DISEASE IS ASSOCIATED WITH ILEAL INVOLVEMENT, NON-INFLAMMATORY DISEASE BEHAVIOUR AND NOD2/CARD15 GENOTYPE, BUT NOT RESPONSE TO MEDICAL THERAPY OR RISK FOR SURGERY

Seroreactivity to microbial components i

Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients

✍ Maria Papp; Istvan Altorjay; Gary L. Norman; Zakera Shums; Karoly Palatka; Zsuzs 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB 👁 2 views

Background: Antibodies directed against Saccharomyces cerevisiae (ASCA), perinuclear components of neutrophils (pANCA), and porin protein C of Escherichia coli (anti-OmpC) are reported to be associated with disease phenotype and may be of diagnostic importance in inflammatory bowel disease (IBD). Si