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P XII.4 - P XII.4 DNA damage induced by the drinking water mutagen MX in vivo and in vitro

✍ Scribed by Gunnar Brunborg; Unni Haddeland; Jørn A. Holme


Book ID
114071809
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
132 KB
Volume
379
Category
Article
ISSN
0027-5107

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The frequency of point mutations in p53 (exons 4 -7) and in Ki-ras, Ha-ras, and N-ras (exons 1 and 2) and the expression of p53 protein were evaluated in the liver tumors of Wistar rats of a 104week carcinogenicity study on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinf