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P XII.10 - P XII.10 Trans-dominance analysis of p53 mutants by a yeast functional assay

โœ Scribed by Gilberto Fronza; Alberto Inga; Sara Cresta; Paola Monti; Anna Aprile; Richard Iggo; Angelo Abbondandolo


Book ID
114071815
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
131 KB
Volume
379
Category
Article
ISSN
0027-5107

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Mutation of the p53 gene is found in about one third of astrocytic brain tumors, and expansion of tumor cell clones containing mutant p53 has been implicated in astrocytic tumor progression. However, admixture of normal cells in astrocytic tumor specimens limits the power of traditional studies of t