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P( i -BuNCH 2 CH 2 ) 3 N: An Efficient Ligand for the Direct α-Arylation of Nitriles with Aryl Bromides

✍ Scribed by You, Jingsong; Verkade, John G.


Book ID
126924426
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
103 KB
Volume
68
Category
Article
ISSN
0022-3263

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Pd/P(i-BuNCH2CH2)3N: an efficient cataly
✍ Sameer Urgaonkar; M. Nagarajan; J.G. Verkade 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 123 KB

Pd(OAc) 2 in combination with the commercially available ligand P(i-BuNCH 2 CH 2 ) 3 N catalyzes the Suzuki cross-coupling reaction of a wide variety of aryl bromides and chlorides with arylboronic acids, affording the desired biaryls in excellent yields. It has also been shown that P(NMe 2 ) 3 can