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p-Glycoprotein expression in malignant melanoma

✍ Scribed by Blandine Fuchs; Hermann Ostmeier; Ludwig Suter

Book ID
112574220
Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
912 KB
Volume
117
Category
Article
ISSN
1432-1335

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Because reversal of multidrug resistance increases chemotoxicity, early detection of low P-glycoprotein expression is clinically relevant for justifying early treatment of those patients that might benefit most from reversal therapy. We elected to score Pglycoprotein in single tumor cells, because t