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P-glycoprotein efflux pump expression and activity in Calu-3 cells

✍ Scribed by Karen O. Hamilton; Gunilla Backstrom; Mehran A. Yazdanian; Kenneth L. Audus


Book ID
101356760
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
257 KB
Volume
90
Category
Article
ISSN
0022-3549

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## Abstract The purpose of this study was to investigate the correlation between mRNA and protein levels for P‐glycoprotein (P‐gp) expressed in various cell lines to validate the estimation of P‐gp activity from its mRNA levels. P‐gp expression levels in various cell monolayers, normal, P‐gp‐induce