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P-6-6 Normal brain 5HT2 receptors in obsessive-compulsive disorder demonstrated by positron emission tomography

✍ Scribed by F. Biver; S. Goldman; B. Gribomont; M. Monclus; P. Danhaut; J. Mendlewicz; F. Lotstra


Book ID
119176361
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
138 KB
Volume
5
Category
Article
ISSN
0924-977X

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## N1-(111C]-Methyl>2-Br-LSD ([llC] -MBL) has been developed as a positron emission tomography (PET) imaging agent for serotonin 5-HT2 receptors. In vitro receptor binding assays with nonradioactive MBL show high-affinity binding to serotonin 5-HT2 receptors (Ki = 0.5 nM), a secondary interaction