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P-515 Gene therapy of mesothelioma with p16 peptide therapy

✍ Scribed by Frizelle, Sandra P.; Tricker, Erin M.; Kratzke, Marian G.; Niehans, Gloria A.; Kratzke, Robert A.

Book ID: 118572211
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 193 KB
Volume: 41
Category: Article
ISSN: 0169-5002
DOI: 10.1016/s0169-5002(03)92482-2

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## Abstract The __p16__ cell cycle inhibitory gene is a potentially critical molecular abnormality in nasopharyngeal carcinoma (NPC). Its expression is silenced through either deletion or promoter methylation in the vast majority of NPC. This in turn is associated with absent or reduced protein exp