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P-486 - Comparison of acute and chronic effect of escitalopram on rem sleep in rats

✍ Scribed by B. Horváth; S. Vas; Z. Kátai; D. Kostyalik; E. Molnár; P. Petschner; X. Gonda; I. Gyertyán; G. Bagdy

Book ID
119572503
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
93 KB
Volume
27
Category
Article
ISSN
0924-9338

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Effects of acute doses of zimelidine on
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✍ Renato B. Reyes; Shirley Y. Hill; David J. Kupfer 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 368 KB

Sleep EEG (7 h) were obtained from 11 rats given 5, 10, and 20 mg/kg zimelidine, and a control dose of saline. Zimelidine significantly suppressed REM sleep, lengthened REM latency, and reduced total sleep time (TST) in a dosedependent manner. Sleep latency was not affected except at the highest dos