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P-4-2 Production of islet cell antibodies (ICA) from peripheral blood lymphocytes by pokeweed mitogen and epstein-barr virus transformation in insulin-dependent diabetic patients

Book ID: 122767994
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 71 KB
Volume: 3
Category: Article
ISSN: 0168-8227
DOI: 10.1016/S0168-8227(87)80094-3

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Islet cell antibodies are usually detected in the sera of almost all Type i (insulin-dependent) diabetic patients within several months after onset of the disease. The antibodies then disappear quite early during the course of the disease. The present study was undertaken to detect islet cell antibo