liver-infiltrating lymphocytes 4 of patients with chronic hepa-A cytotoxic T lymphocyte (CTL) response to the hepatitis C, the role of CTL responses in HCV infection is untitis C virus (HCV) nucleoprotein residues 88-96 that are known. HCV infection frequently persists and is implicated the minimal
P-377 Hepatitis C virus-specific cytotoxic T lymphocyte responses and viral status in chronic hepatitis C virus infection
β Scribed by K Hiroishi; M Kojima; H Kita; H Okamoto; T Moriyama; T Kaneko; K Ando; T Aikawa; S Ohnishi; N Tanaka; K Mitamura; M Imawari
- Book ID
- 113402263
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 119 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0928-4346
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Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes (CTL) have been shown to play a role in host defense and pathogenesis of chronic HCV infection. Our aim was to test the hypothesis that intrahepatic HCV-specific CTL activity may impact subsequent response to interferon alfa (IFN-β£) therapy. O
Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. Although xenotransplantation of immunodeficient mice with hum