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P-347 Effects of 9-cis retinoic acid and synthetic retinoids on the production of TNF-α and no by rat Kupffer cells

✍ Scribed by K Motomura; H Isobe; H Sakai; H Nawata

Book ID: 113402231
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 119 KB
Volume: 3
Category: Article
ISSN: 0928-4346
DOI: 10.1016/0928-4346(95)90642-k

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Kupffer cells play important roles in the development of liver injury by producing cytokines and free radicals. In consequence inhibition of these inflammatory mediators will be one of the targets for treating liver diseases. Retinoids modulate a wide variety of functions of monocytes/macrophages. C