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P-334 Frequent epigenetic inactivation of RASSF1A by Aberrant promoter hypermethylation in primary human lung carcinoma

✍ Scribed by He, Jie; Shao, Kang; Xiao, Zhixiong; Zhang, Dechao; Xiong, Meihua; Huang, Wei; Zhou, Fang; Zhang, Cuiyan; Mba, Ndong


Book ID
118572034
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
191 KB
Volume
41
Category
Article
ISSN
0169-5002

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## Abstract The retinoblastoma protein‐interacting zinc finger gene, __RIZ1__ (GenBank accession number U17838), is involved in chromatin‐mediated gene expression and is also a target for frameshift mutation in microsatellite‐unstable cancers. Methylation of the __RIZ1__ promoter CpG island has bee