Frequent epigenetic inactivation of RIZ1
β
Yasuhiro Oshimo; Naohide Oue; Yoshitsugu Mitani; Hirofumi Nakayama; Yasuhiko Kit
π
Article
π
2004
π
John Wiley and Sons
π
French
β 213 KB
## Abstract The retinoblastoma proteinβinteracting zinc finger gene, __RIZ1__ (GenBank accession number U17838), is involved in chromatinβmediated gene expression and is also a target for frameshift mutation in microsatelliteβunstable cancers. Methylation of the __RIZ1__ promoter CpG island has bee