Systemic and especially splanchnic arterial vasodilation accompany chronic portal hypertension. Different soluble mediators causing this vasodilation have been proposed, the strongest evidence being for nitric oxide (NO). No data exist if structural vascular changes may partly account for this vasod
β¦ LIBER β¦
P-331 Increased production of nitric oxide and its role in the portal circulation in cirrhotic rats
β Scribed by Masaki Mizumato; Shigeki Arii; Masaharu Furutani; Toshio Nakamura; Kazunobu Monden; Satoru Ishiguro; Shinnichi Fujita; Masayuki Imamura
- Book ID
- 113402214
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 123 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0928-4346
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Total portal-systemic shunting in normal animals is associated with splanchnic and systemic vasodilation, suggesting that vasodilation in cirrhosis may be facilitated by spontaneous shunts promoted by portal hypertension. However, the mechanism of this vasodilation is unknown. The aim is to study th