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P-277 Factors predictive of response to interferon therapy in patients with hepatitis C virus infection and analyses of nucleotide and amino acid sequences obtained from treated patients

✍ Scribed by K Chayama; M Kobayashi; A Tsubota; Y Suzuki; Y Arase; I Koida; S Saitoh; N Murashima; K Ikeda; H Kumada; M Kobayashi; H Koike; M Hashimoto

Book ID: 113402165
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 101 KB
Volume: 3
Category: Article
ISSN: 0928-4346
DOI: 10.1016/0928-4346(95)90576-s

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## Abstract Patients with high viral load (≥1.0 × 10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the