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P-225 Modeling of myelodysplasia in a humanized immunodeficient mouse model

✍ Scribed by Halene, S.; Rongvaux, A.; Podoltsev, N.; Kahlon, K.; Manz, M.G.; Flavell, R.A.

Book ID
123072803
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
252 KB
Volume
37
Category
Article
ISSN
0145-2126

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## Abstract Immunodeficient humans are at very high risk of developing Epstein‐Barr virus (EBV)‐induced lymphomagenesis. Severe combined immunodeficient mice (SCID) have been shown to develop lymphoproliferative disease (LPD) following transfer of peripheral blood leukocytes (PBL) with latent EBV.