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P-2-4 The additive effects of quinine on antidepressants in the forced swimming test in mice

✍ Scribed by W.Y. Guo; K. Todd; M. Bourin


Book ID
119176075
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
139 KB
Volume
5
Category
Article
ISSN
0924-977X

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Influence of naloxone on antidepressant
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The influence of naloxone on the effects of several antidepressant drugs, atropine and caffeine was studied in the forced swimming test in mice. Naloxone itself has no effect in this test, but significantly reduces that of two tricyclic antidepressants, clomipramine (20 and 30 mg/kg) and desipramine