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P-135 Hydrogen peroxide mediates ethanol-induced mitochondrial dysfunction in rat hepatocytes

✍ Scribed by K Tomita; I Kurose; H Higuchi; Y Kamegaya; Y Horie; S Kato; S Miura; H Ishii

Book ID
113402019
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
124 KB
Volume
3
Category
Article
ISSN
0928-4346

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Mitochondrial glutathione plays an important role in maintaining a functionally competent organelle. Previous studies have shown that ethanol feeding selectively depletes the mitochondrial glutathione pool, more predominantly in mitochondria from perivenous hepatocytes. Because S-adenosyl-L-methioni