P-106 Prognostic significance of NPM1, CEBPA, and MLL-PTDs mutations, EVI1, MN1 and ERG expressions in MDS and AML treated with azacitidine

Expression and prognostic significance o

Expression and prognostic significance of different mRNA 5′-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration

✍ Katja Haas; Michael Kundi; Wolfgang R. Sperr; Harald Esterbauer; Wolf-Dieter Lud 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 200 KB 👁 2 views

## Abstract Rearrangements of chromosome band 3q26.2 lead to overexpression of the __EVI1__ gene and are associated with a poor prognosis in myeloid malignancies. __EVI1__ is also overexpressed in some cases without 3q26 rearrangements. To uncover its prognostic significance in this patient group,