Oxytocin, Vasopressin, and the Neurogenetics of Sociality

✍ Scribed by Donaldson, Z. R.; Young, L. J.

• Book ID: 118125218
• Publisher: American Association for the Advancement of Science
• Year: 2008
• Tongue: English
• Weight: 301 KB
• Volume: 322
• Category: Article
• ISSN: 0036-8075
• DOI: 10.1126/science.1158668

✦ Synopsis

There is growing evidence that the neuropeptides oxytocin and vasopressin modulate complex social behavior and social cognition. These ancient neuropeptides display a marked conservation in gene structure and expression, yet diversity in the genetic regulation of their receptors seems to underlie natural variation in social behavior, both between and within species. Human studies are beginning to explore the roles of these neuropeptides in social cognition and behavior and suggest that variation in the genes encoding their receptors may contribute to variation in human social behavior by altering brain function. Understanding the neurobiology and neurogenetics of social cognition and behavior has important implications, both clinically and for society.