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Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway

✍ Scribed by Zhang, Yong; Sun, Siguo; Chen, Jun; Ren, Pengcheng; Hu, Yunsheng; Cao, Zhuo; Sun, Honghui; Ding, Yong

Book ID
121544676
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
444 KB
Volume
35
Category
Article
ISSN
1010-4283

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## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su