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Oxygen Induces p53-Dependent NOS3-Mediated Survival Pathway in the Infarct Myocardium by Regulating p53(Lys118) Acetylation and p53 DNA Interaction

✍ Scribed by Gogna, Rajan; Madan, Esha; Khan, Mahmood; Kuppusamy, Periannan

Book ID: 123329993
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 184 KB
Volume: 53
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2012.10.461

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## Abstract DNA damage is known to be an initiator of neuronal death in neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. The mechanism linking DNA damage and neuronal death is not completely understood. Here, we delineate the mechanism by which neuronal death evoked by DNA