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Oxygen-induced retinopathy in the newborn rat: effects of hyperbarism and topical administration of timolol maleate

✍ Scribed by Benedetto Ricci; Giuseppe Minicucci; Alessandra Manfredi; Alessandro Santo

Book ID
112278940
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
933 KB
Volume
233
Category
Article
ISSN
0065-6100

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The effects of timolol maleate on intraocular pressure (IOP) and the severity of retinopathy induced by exposure to 80% oxygen were studied in newborn Wistar rats. One drop of timolol maleate (0.25%) instilled in each eye twice a day for the first ten days of life substantially reduced intraocular p

Oxygen-induced retinopathy in the newbor
Oxygen-induced retinopathy in the newborn rat: a scoring system for the evaluation of retinal vascular changes
✍ Benedetto Ricci; Domenico Lepore; Enrico Zonghi; Giuseppe Calogero πŸ“‚ Article πŸ“… 1991 πŸ› Springer-Verlag 🌐 English βš– 411 KB

The authors describe a scoring system they have developed for evaluating damage produced in the retinal vascular network of the newborn rat by exposure to oxygen. India ink-injected retinal flat mounts are used. The scoring system provides for division of the retina into three concentric zones with