Oxygen-enhanced magnetic resonance ventilation imaging of the human lung at 0.2 and 1.5 T

✍ Scribed by Klaus W. Stock; Qun Chen; Martina Morrin; Hiroto Hatabu; Robert R. Edelman

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 169 KB
• Volume: 9
• Category: Article
• ISSN: 1053-1807
• DOI: 10.1002/(sici)1522-2586(199906)9:6<838::aid-jmri11>3.0.co;2-h

✦ Synopsis

Lung ventilation imaging using inhaled oxygen as a contrast medium was performed using both a 0.2 and a 1.5 T clinical magnetic resonance (MR) scanner in eight volunteers. Signal-to-noise-ratios (SNRs) of the ventilation images as well as T1 values of the lung acquired with inhalation of 100% oxygen and room air were calculated. The SNR was 9.7 ؎ 3.0 on the 0.2 T MR system and 69.5 ؎ 28.8 on the 1.5 T system (P F 0.001). The mean T1 value on the 0.2 T MR system with subjects breathing room air was 632 ؎ 54 msec; with 100% oxygen, it was 586 ؎ 41 msec (P F 0.01). At 1.5 T, the mean values were 904 ؎ 99 msec and 790 ؎ 114 msec, respectively (P F 0.0001). We conclude that MR oxygen-enhanced ventilation imaging of the lung is feasible with an open configured 0.2 T MR system.