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Oxygen consumption and respiratory quotient of caffeinized frog muscles

✍ Scribed by Saslow, George

Publisher
Wiley (John Wiley & Sons)
Year
1937
Tongue
English
Weight
516 KB
Volume
10
Category
Article
ISSN
0095-9898

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✦ Synopsis

ONE FIGURE

Marked changes in twitch tension, initial heat, tension/heat ratio, resting heat rate, and delayed oxidative heat production exhibited by frog muscles treated with subcontracture concentrations of caffeine have been described previously (Saslow, '36 a, b). In the present experiments, the oxygen consumption and respiratory quotient of such muscles have been measured.

The oxygen consumption of unstimulated caffeinized muscles increases as much as twenty-four times and the respiratory quotient rises from 0.89, the average value for normal resting muscle, to 1.00. The increase in oxygen consumption with caffeine is much smaller after treatment with iodoacetate. METHOD8

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## FOUR FIGURES f This paper is based on a dissertation submitted to the Board of University Studies of the Johns Hopkins University in conformity with the requirements for the degree of Doctor of Philosophy ('39). The author wishes to express his gratitude to Prof. 6. 0. hfast under whom this wor