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Oxotechnetium 99mTcO[SN(R)S][S] complexes as potential 5-HT1A receptor imaging agents

✍ Scribed by D Papagiannopoulou; I Pirmettis; Ch Tsoukalas; L Nikoladou; G Drossopoulou; C Dalla; M Pelecanou; Z Papadopoulou-Daifotis; M Papadopoulos; E Chiotellis


Book ID
117687877
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
103 KB
Volume
29
Category
Article
ISSN
0969-8051

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The novel 2-mercaptoimidazole derivatives, 1-[4-((2-methoxyphenyl)-1-piperazinyl)butyl]-2-mercaptoimidazole (3) and methyl[4-((2-methoxyphenyl)-1-piperazinyl))butyl] (2-mercapto-1-methylimidazol-5-yl)methanamide ( 8), were efficiently labelled with 11 C through methylation of the thioketone function