๐”– Bobbio Scriptorium
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Oxo-ester Mediated Native Chemical Ligation: Concept and Applications

โœ Scribed by Wan, Qian; Chen, Jin; Yuan, Yu; Danishefsky, Samuel J.


Book ID
126396295
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
692 KB
Volume
130
Category
Article
ISSN
0002-7863

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Selenocysteine-Mediated Native Chemical
โœ Richard Quaderer; Axel Sewing; Donald Hilvert ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 108 KB

C-Terminal peptide thioesters are shown to react efficiently with peptide fragments containing an Nterminal selenocysteine to give selenoproteins. In analogy to the native chemical ligation of thioesters and peptides containing N-terminal cysteines, the selenol presumably attacks the thioester nucle